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试用ChatGPT Operator 我让它帮我搜索关于司美格鲁肽减肥的论文,尤其是遇到减肥瓶颈期怎么办,然后把标题、提要、URL整理到note [dot] ms上。 它给我找到两篇,期间需要人工干预去验证。 Title: Physiology of the weight-loss plateau in response to diet restriction, GLP-1 receptor agonism, and bariatric surgery Summary: This study investigates weight loss plateaus with different interventions, including semaglutide. It uses a mathematical model to simulate weight loss trajectories and found that RYGB surgery had a more persistent effect than diet restriction and was about double that of tirzepatide and semaglutide. The study indicates that all interventions, except diet restriction, weakened the feedback control circuit, extending the weight loss period before reaching a plateau. Title: Physiology of the Weight Loss Plateau after Calorie Restriction, GLP-1 Receptor Agonism, and Bariatric Surgery (Preprint) Summary: This preprint supports the findings from the previous study, using a mathematical model to simulate weight loss trajectories for different interventions. It concludes that RYGB surgery has a more persistent effect than calorie restriction and is about twice as effective as tirzepatide and semaglutide. All interventions, except calorie restriction, weakened the feedback control circuit, extending the weight loss period before reaching a plateau. Link: Link:

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